Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
fluoxetine neuronal acetylcholine receptor subunit alpha-2 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine neuronal acetylcholine receptor subunit alpha-2 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine neuronal acetylcholine receptor subunit alpha-3 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine neuronal acetylcholine receptor subunit alpha-3 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine neuronal acetylcholine receptor subunit beta-4 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine neuronal acetylcholine receptor subunit beta-4 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine cyclin-dependent kinases regulatory subunit 1 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved unknown
fluoxetine cyclin-dependent kinases regulatory subunit 1 small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved unknown
fluoxetine 5-hydroxytryptamine receptor 2c small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine 5-hydroxytryptamine receptor 2c small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,vet_approved antagonist
fluoxetine potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.02 approved,vet_approved inhibitor
fluoxetine potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.02 approved,vet_approved inhibitor
fluoxetine sodium-dependent serotonin transporter small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved,vet_approved inhibitor
fluoxetine serotonin transporter NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved unknown
fluoxetine sodium-dependent serotonin transporter small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved,vet_approved inhibitor
fluoxetine serotonin transporter NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disease[MeSHID:D004194]
Coronavirus Infections[MeSHID:D018352]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved inhibitor
fluoxetine serotonin transporter NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved inhibitor
fluoxetine serotonin transporter NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Bipolar Disorder[MeSHID:D001714]
Depressive disorder[MeSHID:D003866]
Maintenance[MeSHID:D008283]
Bulimia Nervosa[MeSHID:D052018]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Obsessive compulsive behavior[MeSHID:D003192]
Panic Disorder[MeSHID:D016584]
Depressive Disorder
Treatment-Resistant[MeSHID:D061218]
Mental Depression[MeSHID:D003863]
Agoraphobia[MeSHID:D000379]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved unknown
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