| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| fluorouracil | dihydrothymine dehydrogenase | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
0.74 | approved | unknown |
| fluorouracil | tert messenger rna | NA | Successful target | TTD | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
NA | approved | unknown |
| fluorouracil | thymidylate synthase messenger rna | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
0.23 | approved | inhibitor |
| fluorouracil | thymidylate synthase messenger rna | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
0.23 | approved | unknown |
| fluorouracil | thymidylate synthase | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
0.23 | approved | inhibitor |
| fluorouracil | thymidylate synthase | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
0.23 | approved | unknown |
| fluorouracil | rna | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
NA | approved | incorporation into and destabilization |
| fluorouracil | dna | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Breast[MeSHID:D001940] Biliary tract structure[MeSHID:D001659] Cells[MeSHID:D002477] Basal cell carcinoma[MeSHID:D002280] Actinic keratosis[MeSHID:D055623] Colon structure (body structure)[MeSHID:D003106] Pancreas[MeSHID:D010179] Malignant Neoplasms[MeSHID:D009369] Stomach[MeSHID:D013270] Carcinoid Tumor[MeSHID:D002276] Rectum[MeSHID:D012007] Kidney[MeSHID:D007668] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Neoplasms[MeSHID:D009369] |
NA | approved | incorporation into and destabilization |
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