| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1c | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.67 | approved,investigational | inhibitor,blocker |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1c | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.67 | approved,investigational | inhibitor |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1d | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.52 | approved,investigational | inhibitor,blocker |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1d | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.52 | approved,investigational | inhibitor |
| felodipine | voltage-dependent t-type calcium channel subunit alpha-1h | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | inhibitor |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1s | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.43 | approved,investigational | inhibitor,blocker |
| felodipine | voltage-dependent l-type calcium channel subunit alpha-1s | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.43 | approved,investigational | inhibitor |
| felodipine | voltage-dependent calcium channel subunit alpha-2/delta-1 | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
1.26 | approved,investigational | inhibitor |
| felodipine | voltage-dependent calcium channel subunit alpha-2/delta-2 | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | inhibitor |
| felodipine | voltage-dependent l-type calcium channel subunit beta-2 | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
1.82 | approved,investigational | inhibitor |
| felodipine | calmodulin | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | other |
| felodipine | mineralocorticoid receptor | small molecule | NA | drugbank , DGIDB | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
0.4 | approved,investigational | antagonist |
| felodipine | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1a | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | inhibitor |
| felodipine | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1b | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | inhibitor |
| felodipine | troponin c, slow skeletal and cardiac muscles | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | other |
| felodipine | troponin c, skeletal muscle | small molecule | NA | drugbank | Essential Hypertension[MeSHID:D000075222] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Hypertensive disease[MeSHID:D006973] |
NA | approved,investigational | other |
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