| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| fedratinib | receptor-type tyrosine-protein kinase flt3 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved,investigational | inhibitor |
| fedratinib | receptor-type tyrosine-protein kinase flt3 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Polycythemia Vera[MeSHID:D011087] Disease[MeSHID:D004194] |
0.11 | approved,investigational | inhibitor |
| fedratinib | tyrosine-protein kinase jak1 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.71 | approved,investigational | inhibitor |
| fedratinib | tyrosine-protein kinase jak1 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Polycythemia Vera[MeSHID:D011087] Disease[MeSHID:D004194] |
0.71 | approved,investigational | inhibitor |
| fedratinib | janus kinase 2 | NA | Successful target | TTD , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.31 | approved | unknown |
| fedratinib | tyrosine-protein kinase jak2 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Polycythemia Vera[MeSHID:D011087] Disease[MeSHID:D004194] |
1.31 | approved,investigational | inhibitor |
| fedratinib | tyrosine-protein kinase jak2 | small molecule | NA | drugbank , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.31 | approved,investigational | inhibitor |
| fedratinib | janus kinase 2 | NA | Successful target | TTD , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.31 | approved | inhibitor |
| fedratinib | janus kinase 2 | NA | Successful target | TTD , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Polycythemia Vera[MeSHID:D011087] Disease[MeSHID:D004194] |
1.31 | approved | unknown |
| fedratinib | janus kinase 2 | NA | Successful target | TTD , DGIDB | Primary Myelofibrosis[MeSHID:D055728] Neoplasm Metastasis[MeSHID:D009362] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Polycythemia Vera[MeSHID:D011087] Disease[MeSHID:D004194] |
1.31 | approved | inhibitor |
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