Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
ezetimibe | aminopeptidase n | small molecule | NA | drugbank | Homozygote[MeSHID:D006720] Hyperlipidemia Familial Combined[MeSHID:D006950] Hyperlipidemia[MeSHID:D006949] Sitosterolemia[MeSHID:C537345] Hypercholesterolemia Familial[MeSHID:D006938] Hypercholesterolemia[MeSHID:D006937] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | other |
ezetimibe | niemann-pick c1-like protein 1 | small molecule | Successful target | TTD , drugbank , DGIDB | Homozygote[MeSHID:D006720] Hyperlipidemia Familial Combined[MeSHID:D006950] Hyperlipidemia[MeSHID:D006949] Sitosterolemia[MeSHID:C537345] Hypercholesterolemia Familial[MeSHID:D006938] Hypercholesterolemia[MeSHID:D006937] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
175.04 | approved | inhibitor,antagonist |
ezetimibe | niemann-pick c1-like protein 1 | small molecule | Successful target | TTD , drugbank , DGIDB | Homozygote[MeSHID:D006720] Hyperlipidemia Familial Combined[MeSHID:D006950] Hyperlipidemia[MeSHID:D006949] Sitosterolemia[MeSHID:C537345] Hypercholesterolemia Familial[MeSHID:D006938] Hypercholesterolemia[MeSHID:D006937] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
175.04 | approved | inhibitor |
ezetimibe | sterol o-acyltransferase 1 | small molecule | NA | drugbank | Homozygote[MeSHID:D006720] Hyperlipidemia Familial Combined[MeSHID:D006950] Hyperlipidemia[MeSHID:D006949] Sitosterolemia[MeSHID:C537345] Hypercholesterolemia Familial[MeSHID:D006938] Hypercholesterolemia[MeSHID:D006937] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
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