Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
exisulind aldose reductase small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational inhibitor
exisulind aldo-keto reductase family 1 member b10 small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational inhibitor
exisulind glutathione s-transferase p small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational inhibitor
exisulind cgmp-dependent 3',5'-cyclic phosphodiesterase small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational unknown
exisulind camp-specific 3',5'-cyclic phosphodiesterase 4c small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational unknown
exisulind camp-specific 3',5'-cyclic phosphodiesterase 4d small molecule NA drugbank Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA investigational unknown
exisulind phosphodiesterase 5a NA Successful target TTD , DGIDB Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.88 phase 3 unknown
exisulind cgmp-specific 3',5'-cyclic phosphodiesterase small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Adenomatous Polyposis Coli[MeSHID:D011125]
Malignant neoplasm of prostate[MeSHID:D011471]
Malignant neoplasm of lung[MeSHID:D008175]
Esophagus[MeSHID:D004947]
Colonic Polyps[MeSHID:D003111]
Barrett Esophagus[MeSHID:D001471]
Esophageal Diseases[MeSHID:D004935]
Colorectal Cancer[MeSHID:D015179]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.88 investigational unknown
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