| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| ethotoin | nuclear receptor subfamily 1 group i member 2 | small molecule | NA | drugbank | Epilepsy Temporal Lobe[MeSHID:D004833] Tonic-Clonic Epilepsy[MeSHID:D004830] Tonic - clonic seizures[MeSHID:D012640] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | activator |
| ethotoin | sodium channel protein type 5 subunit alpha | small molecule | NA | drugbank , DGIDB | Epilepsy Temporal Lobe[MeSHID:D004833] Tonic-Clonic Epilepsy[MeSHID:D004830] Tonic - clonic seizures[MeSHID:D012640] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | inhibitor,blocker |
| ethotoin | sodium channel protein type 5 subunit alpha | small molecule | NA | drugbank , DGIDB | Epilepsy Temporal Lobe[MeSHID:D004833] Tonic-Clonic Epilepsy[MeSHID:D004830] Tonic - clonic seizures[MeSHID:D012640] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | inhibitor |
| ethotoin | voltage-gated sodium channel alpha nav1.5 | NA | Successful target | TTD , DGIDB | Epilepsy Temporal Lobe[MeSHID:D004833] Tonic-Clonic Epilepsy[MeSHID:D004830] Tonic - clonic seizures[MeSHID:D012640] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | blocker |
| ethotoin | voltage-gated sodium channel alpha nav1.5 | NA | Successful target | TTD , DGIDB | Epilepsy Temporal Lobe[MeSHID:D004833] Tonic-Clonic Epilepsy[MeSHID:D004830] Tonic - clonic seizures[MeSHID:D012640] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | unknown |
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