| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | ligand |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,illicit | ligand |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,illicit | ligand |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved,illicit | ligand |
| estazolam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved,illicit | ligand,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved,illicit | positive allosteric modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| estazolam | translocator protein | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Accidental Falls[MeSHID:D000058] Early Awakening[MeSHID:D007319] Term Birth[MeSHID:D047929] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | unknown |
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