| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| esketamine | brain-derived neurotrophic factor | small molecule | NA | drugbank | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
NA | approved,investigational | agonist |
| esketamine | elongation factor 2 | small molecule | NA | drugbank | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
NA | approved,investigational | inhibitor |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.42 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.26 | approved,investigational | antagonist |
| esketamine | glutamate receptor ionotropic, nmda 2b | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.4 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.4 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.27 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.28 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.3 | approved,investigational | antagonist |
| esketamine | nmda receptor | small molecule | NA | drugbank , DGIDB | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.38 | approved,investigational | antagonist |
| esketamine | bdnf/nt-3 growth factors receptor | small molecule | NA | drugbank | Depressive Disorder Treatment-Resistant[MeSHID:D061218] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
NA | approved,investigational | unknown |
| click here to return to the previous page | ||||||||