| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| escitalopram | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | dopamine d2 receptor | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | histamine h1 receptor | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.07 | approved | inhibitor |
| escitalopram | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | inhibitor |
| escitalopram | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | sodium-dependent dopamine transporter | small molecule | NA | drugbank | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| escitalopram | serotonin transporter | NA | Successful target | TTD , DGIDB | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.72 | approved | unknown |
| escitalopram | serotonin transporter | NA | Successful target | TTD , DGIDB | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.72 | approved | inhibitor |
| escitalopram | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] Maintenance[MeSHID:D008283] Obsessive compulsive behavior[MeSHID:D003192] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.72 | approved | inhibitor |
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