| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| ergotamine | alpha-1a adrenergic receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | partial agonist |
| ergotamine | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | partial agonist |
| ergotamine | alpha-1d adrenergic receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | partial agonist |
| ergotamine | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | partial agonist |
| ergotamine | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | unknown |
| ergotamine | d(1) dopamine receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | agonist |
| ergotamine | dopamine d2 receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | agonist |
| ergotamine | d(1) dopamine receptor | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
NA | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.65 | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.94 | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 1f | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.49 | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.19 | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.21 | approved | agonist |
| ergotamine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Cluster Headache[MeSHID:D003027] Vascular Headaches[MeSHID:D014653] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Headache[MeSHID:D006261] |
0.15 | approved | agonist |
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