| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| enzastaurin | rac-alpha serine/threonine-protein kinase | small molecule | Clinical trial target | TTD , drugbank , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
0.1 | investigational,phase 3 | unknown |
| enzastaurin | aurora kinase a | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | aurora kinase b | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | cyclin-dependent kinase 15 | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | serine/threonine-protein kinase chk1 | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | serine/threonine-protein kinase chk2 | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | pi3-kinase gamma | NA | Successful target | TTD , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
0.07 | phase 3 | unknown |
| enzastaurin | phosphatidylinositol 3-kinase regulatory subunit alpha | small molecule | NA | drugbank | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
NA | investigational | unknown |
| enzastaurin | protein kinase c beta type | small molecule | NA | drugbank , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
2.83 | investigational | unknown |
| enzastaurin | protein kinase c beta | NA | Clinical trial target | TTD , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
2.83 | phase 3 | inhibitor |
| enzastaurin | protein kinase c beta type | small molecule | NA | drugbank , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
2.83 | investigational | inhibitor |
| enzastaurin | protein kinase c beta | NA | Clinical trial target | TTD , DGIDB | Lymphoma[MeSHID:D008223] Lymphoma Non-Hodgkin[MeSHID:D008228] Malignant neoplasm of brain[MeSHID:D001932] Malignant neoplasm of lung[MeSHID:D008175] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Diffuse Large B-Cell Lymphoma[MeSHID:D016403] Glioblastoma[MeSHID:D005909] |
2.83 | phase 3 | unknown |
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