| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| enrasentan | endothelin-1 receptor | small molecule | NA | drugbank , DGIDB | Chronic Obstructive Airway Disease[MeSHID:D029424] Benign Prostatic Hyperplasia[MeSHID:D011470] Congestive heart failure[MeSHID:D006333] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
3.54 | investigational | antagonist |
| enrasentan | endothelin a receptor | NA | Successful target | TTD , DGIDB | Chronic Obstructive Airway Disease[MeSHID:D029424] Benign Prostatic Hyperplasia[MeSHID:D011470] Congestive heart failure[MeSHID:D006333] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
3.54 | discontinued in phase 2 | antagonist |
| enrasentan | endothelin b receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Chronic Obstructive Airway Disease[MeSHID:D029424] Benign Prostatic Hyperplasia[MeSHID:D011470] Congestive heart failure[MeSHID:D006333] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
6.37 | investigational,discontinued in phase 2 | antagonist |
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