Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
emapalumab interferon-gamma NA Successful target TTD , DGIDB Disease[MeSHID:D004194]
Cessation of life[MeSHID:D003643]
macrophage[MeSHID:D008264]
Lymphohistiocytosis
Hemophagocytic[MeSHID:D051359]
Fever[MeSHID:D005334]
Intrinsic drive[MeSHID:D004328]
Hepatomegaly[MeSHID:D006529]
Spleen[MeSHID:D013154]
T-Lymphocyte[MeSHID:D013601]
Thinking
function[MeSHID:D013850]
Recurrence (disease attribute)[MeSHID:D012008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Familial Hemophagocytic Lymphocytosis[MeSHID:D051359]
Coronavirus Infections[MeSHID:D018352]		 0.94 approved unknown
emapalumab interferon-gamma NA Successful target TTD , DGIDB Disease[MeSHID:D004194]
Cessation of life[MeSHID:D003643]
macrophage[MeSHID:D008264]
Lymphohistiocytosis
Hemophagocytic[MeSHID:D051359]
Fever[MeSHID:D005334]
Intrinsic drive[MeSHID:D004328]
Hepatomegaly[MeSHID:D006529]
Spleen[MeSHID:D013154]
T-Lymphocyte[MeSHID:D013601]
Thinking
function[MeSHID:D013850]
Recurrence (disease attribute)[MeSHID:D012008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Familial Hemophagocytic Lymphocytosis[MeSHID:D051359]		 0.94 approved unknown
emapalumab interferon gamma biotech NA drugbank , DGIDB Disease[MeSHID:D004194]
Cessation of life[MeSHID:D003643]
macrophage[MeSHID:D008264]
Lymphohistiocytosis
Hemophagocytic[MeSHID:D051359]
Fever[MeSHID:D005334]
Intrinsic drive[MeSHID:D004328]
Hepatomegaly[MeSHID:D006529]
Spleen[MeSHID:D013154]
T-Lymphocyte[MeSHID:D013601]
Thinking
function[MeSHID:D013850]
Recurrence (disease attribute)[MeSHID:D012008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Familial Hemophagocytic Lymphocytosis[MeSHID:D051359]		 0.94 approved,investigational neutralizer
emapalumab interferon gamma biotech NA drugbank , DGIDB Disease[MeSHID:D004194]
Cessation of life[MeSHID:D003643]
macrophage[MeSHID:D008264]
Lymphohistiocytosis
Hemophagocytic[MeSHID:D051359]
Fever[MeSHID:D005334]
Intrinsic drive[MeSHID:D004328]
Hepatomegaly[MeSHID:D006529]
Spleen[MeSHID:D013154]
T-Lymphocyte[MeSHID:D013601]
Thinking
function[MeSHID:D013850]
Recurrence (disease attribute)[MeSHID:D012008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Familial Hemophagocytic Lymphocytosis[MeSHID:D051359]
Coronavirus Infections[MeSHID:D018352]		 0.94 approved,investigational neutralizer
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