Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
doxepin | alpha-1a adrenergic receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
doxepin | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
doxepin | alpha-1d adrenergic receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
doxepin | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,investigational | antagonist |
doxepin | muscarinic acetylcholine receptor m2 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved,investigational | antagonist |
doxepin | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved,investigational | antagonist |
doxepin | muscarinic acetylcholine receptor m4 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.24 | approved,investigational | antagonist |
doxepin | muscarinic acetylcholine receptor m5 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,investigational | antagonist |
doxepin | histamine h1 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.34 | approved,investigational | antagonist |
doxepin | histamine h2 receptor | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.41 | approved,investigational | antagonist |
doxepin | histamine h4 receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | binder |
doxepin | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
doxepin | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved,investigational | antagonist |
doxepin | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved,investigational | antagonist |
doxepin | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved,investigational | antagonist |
doxepin | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | binder |
doxepin | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.02 | approved,investigational | inhibitor |
doxepin | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.36 | approved,investigational | inhibitor |
doxepin | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Disease Management[MeSHID:D019468] Involutional Depression[MeSHID:D003865] Eczema[MeSHID:D004485] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Physical Examination[MeSHID:D010808] Phobic anxiety disorder[MeSHID:D010698] Post-Traumatic Stress Disorder[MeSHID:D013313] Sleep Disorders[MeSHID:D012893] Affect (mental function)[MeSHID:D000339] Panic[MeSHID:D010200] Nociceptors[MeSHID:D009619] Anxiety Disorders[MeSHID:D001008] Lichen Simplex Chronicus[MeSHID:D009450] Obsessive-Compulsive Disorder[MeSHID:D009771] Mental Depression[MeSHID:D003863] Sleep[MeSHID:D012890] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Pruritus[MeSHID:D011537] Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Disease[MeSHID:D004194] Neuralgia[MeSHID:D009437] Alcoholic Intoxication Chronic[MeSHID:D000437] Obsessive compulsive behavior[MeSHID:D003192] Dermatitis Atopic[MeSHID:D003876] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.3 | approved,investigational | inhibitor |
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