Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
dorzolamide carbonic anhydrase 1 small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Eye[MeSHID:D005123]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.89 approved inhibitor
dorzolamide carbonic anhydrase ii NA Successful target TTD , DGIDB Disease Management[MeSHID:D019468]
Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Eye[MeSHID:D005123]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 6.64 approved unknown
dorzolamide carbonic anhydrase 2 small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Eye[MeSHID:D005123]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 6.64 approved inhibitor
dorzolamide carbonic anhydrase 3 small molecule NA drugbank Disease Management[MeSHID:D019468]
Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Eye[MeSHID:D005123]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
dorzolamide carbonic anhydrase 4 small molecule NA drugbank Disease Management[MeSHID:D019468]
Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Eye[MeSHID:D005123]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
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