| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| dopamine | dopamine beta-hydroxylase | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | ligand |
| dopamine | d(1) dopamine receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.14 | approved | agonist |
| dopamine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.14 | approved | agonist |
| dopamine | dopamine d2 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.07 | approved | agonist |
| dopamine | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.07 | approved | agonist |
| dopamine | dopamine d4 receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.09 | approved | agonist |
| dopamine | d(1) dopamine receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.18 | approved | agonist |
| dopamine | dopamine d5 receptor | small molecule | NA | drugbank , DGIDB | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.18 | approved | agonist |
| dopamine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | binder |
| dopamine | 5-hydroxytryptamine receptor 3a | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | unknown |
| dopamine | 5-hydroxytryptamine receptor 3b | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | unknown |
| dopamine | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | binder |
| dopamine | synaptic vesicular amine transporter | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | unknown |
| dopamine | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | inhibitor |
| dopamine | sodium-dependent dopamine transporter | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | inducer |
| dopamine | sodium-dependent serotonin transporter | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | inhibitor |
| dopamine | superoxide dismutase [cu-zn] | small molecule | NA | drugbank | Sepsis[MeSHID:D018805] Kidney Failure[MeSHID:D051437] Heart Decompensation[MeSHID:D006333] Traumatic injury[MeSHID:D014947] Hemodynamics[MeSHID:D006439] Shock[MeSHID:D012769] Myocardial Infarction[MeSHID:D009203] Hypotension[MeSHID:D007022] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved | unknown |
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