| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| donepezil | acetylcholinesterase | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
3.33 | approved | inhibitor |
| donepezil | cholinesterase | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
5.2 | approved | inducer |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | downregulator |
| donepezil | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inducer |
| donepezil | interleukin-1 beta | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor,inducer |
| donepezil | nuclear factor nf-kappa-b | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| donepezil | nuclear factor nf-kappa-b | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| donepezil | nitric oxide synthase, brain | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor,inducer |
| donepezil | tumor necrosis factor-inducible gene 6 protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Lewy Body Disease[MeSHID:D020961] ALZHEIMER DISEASE 10[MeSHID:C566465] Dementia Vascular[MeSHID:D015140] Parkinson Disease[MeSHID:D010300] Patient Discharge[MeSHID:D010351] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
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