| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| disopyramide | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | antagonist |
| disopyramide | muscarinic acetylcholine receptor m2 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | antagonist |
| disopyramide | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | antagonist |
| disopyramide | potassium voltage-gated channel subfamily d member 2 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | inhibitor |
| disopyramide | potassium voltage-gated channel subfamily d member 3 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | inhibitor |
| disopyramide | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
0.31 | approved | inhibitor,blocker |
| disopyramide | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
0.31 | approved | inhibitor |
| disopyramide | alpha-1-acid glycoprotein 2 | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
NA | approved | unknown |
| disopyramide | voltage-gated sodium channel alpha nav1.5 | NA | Successful target | TTD , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
1.91 | approved | unknown |
| disopyramide | sodium channel protein type 5 subunit alpha | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Conduction disorder of the heart[MeSHID:D000075224] Preexcitation Syndrome[MeSHID:D011226] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Urinary Incontinence[MeSHID:D014549] |
1.91 | approved | inhibitor |
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