Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
diltiazem voltage-dependent l-type calcium channel subunit alpha-1c small molecule NA drugbank , DGIDB Cardiomyopathy
Familial Idiopathic[MeSHID:D002311]
Tachycardia
Atrioventricular Nodal Reentry[MeSHID:D013611]
Systemic arterial pressure[MeSHID:D062186]
Disease Management[MeSHID:D019468]
Reciprocating[MeSHID:D054139]
Heart Atrium[MeSHID:D006325]
Atrial Flutter[MeSHID:D001282]
Blood Pressure[MeSHID:D001794]
Exercise Tolerance[MeSHID:D017079]
Wolff-Parkinson-White Syndrome[MeSHID:D014927]
Anal Fissure[MeSHID:D005401]
Supraventricular tachycardia[MeSHID:D013617]
SHORT syndrome[MeSHID:C537327]
Stable angina[MeSHID:D060050]
Proteinuria[MeSHID:D011507]
Pulmonary Hypertension[MeSHID:D006976]
pathologic fistula[MeSHID:D005402]
Accessory Atrioventricular Bundle (disorder)[MeSHID:D058606]
Term Birth[MeSHID:D047929]
Hypertensive disease[MeSHID:D006973]
Ventricular Flutter[MeSHID:D054141]
Diabetic Nephropathy[MeSHID:D003928]
Muscle Cramp[MeSHID:D009120]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Angina Pectoris
Variant[MeSHID:D000788]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.31 approved,investigational blocker
diltiazem voltage-gated calcium channel alpha-2/delta-1 NA Successful target TTD , DGIDB Cardiomyopathy
Familial Idiopathic[MeSHID:D002311]
Tachycardia
Atrioventricular Nodal Reentry[MeSHID:D013611]
Systemic arterial pressure[MeSHID:D062186]
Disease Management[MeSHID:D019468]
Reciprocating[MeSHID:D054139]
Heart Atrium[MeSHID:D006325]
Atrial Flutter[MeSHID:D001282]
Blood Pressure[MeSHID:D001794]
Exercise Tolerance[MeSHID:D017079]
Wolff-Parkinson-White Syndrome[MeSHID:D014927]
Anal Fissure[MeSHID:D005401]
Supraventricular tachycardia[MeSHID:D013617]
SHORT syndrome[MeSHID:C537327]
Stable angina[MeSHID:D060050]
Proteinuria[MeSHID:D011507]
Pulmonary Hypertension[MeSHID:D006976]
pathologic fistula[MeSHID:D005402]
Accessory Atrioventricular Bundle (disorder)[MeSHID:D058606]
Term Birth[MeSHID:D047929]
Hypertensive disease[MeSHID:D006973]
Ventricular Flutter[MeSHID:D054141]
Diabetic Nephropathy[MeSHID:D003928]
Muscle Cramp[MeSHID:D009120]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Angina Pectoris
Variant[MeSHID:D000788]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.29 approved unknown
diltiazem voltage-dependent calcium channel gamma-1 subunit small molecule NA drugbank , DGIDB Cardiomyopathy
Familial Idiopathic[MeSHID:D002311]
Tachycardia
Atrioventricular Nodal Reentry[MeSHID:D013611]
Systemic arterial pressure[MeSHID:D062186]
Disease Management[MeSHID:D019468]
Reciprocating[MeSHID:D054139]
Heart Atrium[MeSHID:D006325]
Atrial Flutter[MeSHID:D001282]
Blood Pressure[MeSHID:D001794]
Exercise Tolerance[MeSHID:D017079]
Wolff-Parkinson-White Syndrome[MeSHID:D014927]
Anal Fissure[MeSHID:D005401]
Supraventricular tachycardia[MeSHID:D013617]
SHORT syndrome[MeSHID:C537327]
Stable angina[MeSHID:D060050]
Proteinuria[MeSHID:D011507]
Pulmonary Hypertension[MeSHID:D006976]
pathologic fistula[MeSHID:D005402]
Accessory Atrioventricular Bundle (disorder)[MeSHID:D058606]
Term Birth[MeSHID:D047929]
Hypertensive disease[MeSHID:D006973]
Ventricular Flutter[MeSHID:D054141]
Diabetic Nephropathy[MeSHID:D003928]
Muscle Cramp[MeSHID:D009120]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Angina Pectoris
Variant[MeSHID:D000788]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.45 approved,investigational blocker
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