Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
dequalinium cgmp-gated cation channel alpha-1 small molecule NA drugbank , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 15.91 approved,investigational blocker
dequalinium cyclic nucleotide-gated channel alpha-1 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 15.91 clinical trial blocker
dequalinium cyclic nucleotide-gated channel alpha-1 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 15.91 clinical trial unknown
dequalinium cyclic nucleotide-gated channel alpha-2 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 10.61 clinical trial blocker
dequalinium cyclic nucleotide-gated channel alpha-2 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 10.61 clinical trial unknown
dequalinium calcium-activated potassium channel subunit alpha-1 small molecule NA drugbank Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
dequalinium calcium-activated potassium channel kca2.1 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.12 clinical trial blocker
dequalinium calcium-activated potassium channel kca2.1 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.12 clinical trial unknown
dequalinium calcium-activated potassium channel kca2.2 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.77 clinical trial unknown
dequalinium calcium-activated potassium channel kca2.3 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.65 clinical trial unknown
dequalinium calcium-activated potassium channel kca2.3 NA Clinical trial target TTD , DGIDB Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.65 clinical trial blocker
dequalinium e3 ubiquitin-protein ligase xiap small molecule NA drugbank Bacterial Vaginosis[MeSHID:D016585]
Trichomonas Infections[MeSHID:D014245]
Vaginitis[MeSHID:D014627]
Vaginal Discharge[MeSHID:D019522]
Infection[MeSHID:D007239]
Vulva[MeSHID:D014844]
Candidiasis of vagina[MeSHID:D002181]
Bone Marrow Diseases[MeSHID:D001855]
Spinal Cord Diseases[MeSHID:D013118]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational antagonist,inhibitor
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