Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
darifenacin muscarinic acetylcholine receptor m1 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Overactive Bladder[MeSHID:D053201]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.29 approved,investigational antagonist
darifenacin muscarinic acetylcholine receptor m2 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Overactive Bladder[MeSHID:D053201]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.38 approved,investigational antagonist
darifenacin muscarinic acetylcholine receptor m3 small molecule Successful target TTD , drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Overactive Bladder[MeSHID:D053201]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.85 approved,investigational antagonist
darifenacin muscarinic acetylcholine receptor m4 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Overactive Bladder[MeSHID:D053201]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.54 approved,investigational antagonist
darifenacin muscarinic acetylcholine receptor m5 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Overactive Bladder[MeSHID:D053201]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.5 approved,investigational antagonist
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