| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| danazol | androgen receptor | small molecule | NA | drugbank , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
0.03 | approved | agonist |
| danazol | c-c motif chemokine 2 | small molecule | NA | drugbank | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
NA | approved | inhibitor |
| danazol | estrogen receptor alpha | small molecule | NA | drugbank , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
0.16 | approved | agonist |
| danazol | estrogen receptor | NA | Successful target | TTD , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
0.16 | approved | unknown |
| danazol | gonadotropin-releasing hormone receptor | small molecule | NA | drugbank , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
0.66 | approved | negative modulator |
| danazol | putative gonadotropin-releasing hormone ii receptor | small molecule | NA | drugbank , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
2.98 | approved | negative modulator |
| danazol | progesterone receptor | small molecule | NA | drugbank , DGIDB | Breast Fibrocystic Disease[MeSHID:D005348] Angioedemas Hereditary[MeSHID:D054179] Endometriosis[MeSHID:D004715] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Menorrhagia[MeSHID:D008595] Malignant neoplasm of breast[MeSHID:D001943] |
0.36 | approved | agonist |
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