Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
dacomitinib epidermal growth factor receptor small molecule Successful target TTD , drugbank , DGIDB Malignant Neoplasms[MeSHID:D009369]
lymph nodes[MeSHID:D008198]
Disease[MeSHID:D004194]
Mutation[MeSHID:D009154]
Neoplasm Metastasis[MeSHID:D009362]
Cause of Death[MeSHID:D002423]
Malignant neoplasm of lung[MeSHID:D008175]
Non-Small Cell Lung Carcinoma[MeSHID:D002289]
Missense Mutation[MeSHID:D020125]
Deletion Mutation[MeSHID:D017384]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.07 approved,investigational inhibitor
dacomitinib erbb2 tyrosine kinase receptor NA Successful target TTD , DGIDB Malignant Neoplasms[MeSHID:D009369]
lymph nodes[MeSHID:D008198]
Disease[MeSHID:D004194]
Mutation[MeSHID:D009154]
Neoplasm Metastasis[MeSHID:D009362]
Cause of Death[MeSHID:D002423]
Malignant neoplasm of lung[MeSHID:D008175]
Non-Small Cell Lung Carcinoma[MeSHID:D002289]
Missense Mutation[MeSHID:D020125]
Deletion Mutation[MeSHID:D017384]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.2 approved inhibitor
dacomitinib erbb2 tyrosine kinase receptor NA Successful target TTD , DGIDB Malignant Neoplasms[MeSHID:D009369]
lymph nodes[MeSHID:D008198]
Disease[MeSHID:D004194]
Mutation[MeSHID:D009154]
Neoplasm Metastasis[MeSHID:D009362]
Cause of Death[MeSHID:D002423]
Malignant neoplasm of lung[MeSHID:D008175]
Non-Small Cell Lung Carcinoma[MeSHID:D002289]
Missense Mutation[MeSHID:D020125]
Deletion Mutation[MeSHID:D017384]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.2 approved unknown
dacomitinib erbb4 tyrosine kinase receptor NA Successful target TTD , DGIDB Malignant Neoplasms[MeSHID:D009369]
lymph nodes[MeSHID:D008198]
Disease[MeSHID:D004194]
Mutation[MeSHID:D009154]
Neoplasm Metastasis[MeSHID:D009362]
Cause of Death[MeSHID:D002423]
Malignant neoplasm of lung[MeSHID:D008175]
Non-Small Cell Lung Carcinoma[MeSHID:D002289]
Missense Mutation[MeSHID:D020125]
Deletion Mutation[MeSHID:D017384]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.01 approved inhibitor
dacomitinib erbb4 tyrosine kinase receptor NA Successful target TTD , DGIDB Malignant Neoplasms[MeSHID:D009369]
lymph nodes[MeSHID:D008198]
Disease[MeSHID:D004194]
Mutation[MeSHID:D009154]
Neoplasm Metastasis[MeSHID:D009362]
Cause of Death[MeSHID:D002423]
Malignant neoplasm of lung[MeSHID:D008175]
Non-Small Cell Lung Carcinoma[MeSHID:D002289]
Missense Mutation[MeSHID:D020125]
Deletion Mutation[MeSHID:D017384]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.01 approved unknown
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