| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| cytisine | neuronal acetylcholine receptor alpha-2 | NA | Successful target | TTD , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.64 | phase 3 | unknown |
| cytisine | neuronal acetylcholine receptor subunit alpha-3 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
NA | experimental | agonist |
| cytisine | neuronal acetylcholine receptor alpha-4 | NA | Successful target | TTD , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.93 | phase 3 | unknown |
| cytisine | neuronal acetylcholine receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.93 | experimental | agonist |
| cytisine | neuronal acetylcholine receptor subunit alpha-6 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
NA | experimental | agonist |
| cytisine | neuronal acetylcholine receptor subunit alpha-7 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.87 | experimental | agonist |
| cytisine | neuronal acetylcholine receptor alpha-7 | NA | Successful target | TTD , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.87 | phase 3 | unknown |
| cytisine | neuronal acetylcholine receptor subunit beta-2 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
1.59 | experimental | partial agonist |
| cytisine | neuronal acetylcholine receptor beta-2 | NA | Clinical trial target | TTD , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
1.59 | phase 3 | unknown |
| cytisine | neuronal acetylcholine receptor beta-4 | NA | Clinical trial target | TTD , DGIDB | Cessation of smoking[MeSHID:D016540] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Tobacco Dependence[MeSHID:D014029] |
0.98 | phase 3 | unknown |
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