Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
cyclosporine | calcium signal-modulating cyclophilin ligand | small molecule | NA | drugbank , DGIDB | Eczema[MeSHID:D004485] Graft-vs-Host Disease[MeSHID:D006086] Rupture[MeSHID:D012421] Keratoconjunctivitis Vernal[MeSHID:D003233] Eye[MeSHID:D005123] Nephrotic Syndrome[MeSHID:D009404] Connective Tissue Diseases[MeSHID:D003240] Kidney[MeSHID:D007668] Juvenile arthritis[MeSHID:D001171] Senile Plaques[MeSHID:D058225] Mental Suffering[MeSHID:D013315] Immune thrombocytopenic purpura[MeSHID:D016553] Psoriasis[MeSHID:D011565] Keratoconjunctivitis Sicca[MeSHID:D007638] Liver[MeSHID:D008099] Rheumatoid Arthritis[MeSHID:D001172] Segmental glomerulosclerosis[MeSHID:C538457] Dental Plaque[MeSHID:D003773] Membranous glomerulonephritis[MeSHID:D015433] Bulla[MeSHID:D001768] Tears body substance[MeSHID:D013666] Lipoid nephrosis[MeSHID:D009402] Ulcerative Colitis[MeSHID:D003093] Immunocompromised Host[MeSHID:D016867] Disease[MeSHID:D004194] Graft Rejection[MeSHID:D006084] Dry Eye Syndromes[MeSHID:D015352] Kidney Glomerulus[MeSHID:D007678] Dermatitis Atopic[MeSHID:D003876] Laceration[MeSHID:D022125] Uveitis[MeSHID:D014605] |
9.24 | approved,investigational,vet_approved | binder |
cyclosporine | peptidyl-prolyl cis-trans isomerase a | small molecule | NA | drugbank , DGIDB | Eczema[MeSHID:D004485] Graft-vs-Host Disease[MeSHID:D006086] Rupture[MeSHID:D012421] Keratoconjunctivitis Vernal[MeSHID:D003233] Eye[MeSHID:D005123] Nephrotic Syndrome[MeSHID:D009404] Connective Tissue Diseases[MeSHID:D003240] Kidney[MeSHID:D007668] Juvenile arthritis[MeSHID:D001171] Senile Plaques[MeSHID:D058225] Mental Suffering[MeSHID:D013315] Immune thrombocytopenic purpura[MeSHID:D016553] Psoriasis[MeSHID:D011565] Keratoconjunctivitis Sicca[MeSHID:D007638] Liver[MeSHID:D008099] Rheumatoid Arthritis[MeSHID:D001172] Segmental glomerulosclerosis[MeSHID:C538457] Dental Plaque[MeSHID:D003773] Membranous glomerulonephritis[MeSHID:D015433] Bulla[MeSHID:D001768] Tears body substance[MeSHID:D013666] Lipoid nephrosis[MeSHID:D009402] Ulcerative Colitis[MeSHID:D003093] Immunocompromised Host[MeSHID:D016867] Disease[MeSHID:D004194] Graft Rejection[MeSHID:D006084] Dry Eye Syndromes[MeSHID:D015352] Kidney Glomerulus[MeSHID:D007678] Dermatitis Atopic[MeSHID:D003876] Laceration[MeSHID:D022125] Uveitis[MeSHID:D014605] |
2.82 | approved,investigational,vet_approved | inhibitor,binder,modulator |
cyclosporine | peptidyl-prolyl cis-trans isomerase a | small molecule | NA | drugbank , DGIDB | Eczema[MeSHID:D004485] Graft-vs-Host Disease[MeSHID:D006086] Rupture[MeSHID:D012421] Keratoconjunctivitis Vernal[MeSHID:D003233] Eye[MeSHID:D005123] Nephrotic Syndrome[MeSHID:D009404] Connective Tissue Diseases[MeSHID:D003240] Kidney[MeSHID:D007668] Juvenile arthritis[MeSHID:D001171] Senile Plaques[MeSHID:D058225] Mental Suffering[MeSHID:D013315] Immune thrombocytopenic purpura[MeSHID:D016553] Psoriasis[MeSHID:D011565] Keratoconjunctivitis Sicca[MeSHID:D007638] Liver[MeSHID:D008099] Rheumatoid Arthritis[MeSHID:D001172] Segmental glomerulosclerosis[MeSHID:C538457] Dental Plaque[MeSHID:D003773] Membranous glomerulonephritis[MeSHID:D015433] Bulla[MeSHID:D001768] Tears body substance[MeSHID:D013666] Lipoid nephrosis[MeSHID:D009402] Ulcerative Colitis[MeSHID:D003093] Immunocompromised Host[MeSHID:D016867] Disease[MeSHID:D004194] Graft Rejection[MeSHID:D006084] Dry Eye Syndromes[MeSHID:D015352] Kidney Glomerulus[MeSHID:D007678] Dermatitis Atopic[MeSHID:D003876] Laceration[MeSHID:D022125] Uveitis[MeSHID:D014605] |
2.82 | approved,investigational,vet_approved | inhibitor,binder |
cyclosporine | peptidyl-prolyl cis-trans isomerase f, mitochondrial | small molecule | NA | drugbank | Eczema[MeSHID:D004485] Graft-vs-Host Disease[MeSHID:D006086] Rupture[MeSHID:D012421] Keratoconjunctivitis Vernal[MeSHID:D003233] Eye[MeSHID:D005123] Nephrotic Syndrome[MeSHID:D009404] Connective Tissue Diseases[MeSHID:D003240] Kidney[MeSHID:D007668] Juvenile arthritis[MeSHID:D001171] Senile Plaques[MeSHID:D058225] Mental Suffering[MeSHID:D013315] Immune thrombocytopenic purpura[MeSHID:D016553] Psoriasis[MeSHID:D011565] Keratoconjunctivitis Sicca[MeSHID:D007638] Liver[MeSHID:D008099] Rheumatoid Arthritis[MeSHID:D001172] Segmental glomerulosclerosis[MeSHID:C538457] Dental Plaque[MeSHID:D003773] Membranous glomerulonephritis[MeSHID:D015433] Bulla[MeSHID:D001768] Tears body substance[MeSHID:D013666] Lipoid nephrosis[MeSHID:D009402] Ulcerative Colitis[MeSHID:D003093] Immunocompromised Host[MeSHID:D016867] Disease[MeSHID:D004194] Graft Rejection[MeSHID:D006084] Dry Eye Syndromes[MeSHID:D015352] Kidney Glomerulus[MeSHID:D007678] Dermatitis Atopic[MeSHID:D003876] Laceration[MeSHID:D022125] Uveitis[MeSHID:D014605] |
NA | approved,investigational,vet_approved | binder |
cyclosporine | calcineurin subunit b type 2 | small molecule | NA | drugbank , DGIDB | Eczema[MeSHID:D004485] Graft-vs-Host Disease[MeSHID:D006086] Rupture[MeSHID:D012421] Keratoconjunctivitis Vernal[MeSHID:D003233] Eye[MeSHID:D005123] Nephrotic Syndrome[MeSHID:D009404] Connective Tissue Diseases[MeSHID:D003240] Kidney[MeSHID:D007668] Juvenile arthritis[MeSHID:D001171] Senile Plaques[MeSHID:D058225] Mental Suffering[MeSHID:D013315] Immune thrombocytopenic purpura[MeSHID:D016553] Psoriasis[MeSHID:D011565] Keratoconjunctivitis Sicca[MeSHID:D007638] Liver[MeSHID:D008099] Rheumatoid Arthritis[MeSHID:D001172] Segmental glomerulosclerosis[MeSHID:C538457] Dental Plaque[MeSHID:D003773] Membranous glomerulonephritis[MeSHID:D015433] Bulla[MeSHID:D001768] Tears body substance[MeSHID:D013666] Lipoid nephrosis[MeSHID:D009402] Ulcerative Colitis[MeSHID:D003093] Immunocompromised Host[MeSHID:D016867] Disease[MeSHID:D004194] Graft Rejection[MeSHID:D006084] Dry Eye Syndromes[MeSHID:D015352] Kidney Glomerulus[MeSHID:D007678] Dermatitis Atopic[MeSHID:D003876] Laceration[MeSHID:D022125] Uveitis[MeSHID:D014605] |
7.19 | approved,investigational,vet_approved | inhibitor |
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