| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| clozapine | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.02 | approved | antagonist |
| clozapine | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.02 | approved | antagonist |
| clozapine | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | neuron-specific vesicular protein calcyon | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| clozapine | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.02 | approved | antagonist,allosteric modulator |
| clozapine | muscarinic acetylcholine receptor m2 | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | muscarinic acetylcholine receptor m4 | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | muscarinic acetylcholine receptor m5 | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| clozapine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved | antagonist |
| clozapine | dopamine d2 receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved | antagonist |
| clozapine | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved | antagonist |
| clozapine | dopamine d4 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | antagonist |
| clozapine | glutathione s-transferase p | small molecule | NA | drugbank | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| clozapine | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved | antagonist |
| clozapine | histamine h4 receptor | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | antagonist,agonist |
| clozapine | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved | antagonist,agonist |
| clozapine | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved | antagonist,agonist |
| clozapine | 5-hydroxytryptamine receptor 1e | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved | antagonist,agonist |
| clozapine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 3a | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved | antagonist |
| clozapine | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank , DGIDB | Schizophrenia[MeSHID:D012559] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | antagonist |
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