Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
clomipramine | glutathione s-transferase p | small molecule | NA | drugbank | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational,vet_approved | inhibitor |
clomipramine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational,vet_approved | antagonist |
clomipramine | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational,vet_approved | antagonist |
clomipramine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational,vet_approved | antagonist |
clomipramine | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.5 | approved,investigational,vet_approved | inhibitor |
clomipramine | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1 | approved,investigational,vet_approved | inhibitor |
clomipramine | serotonin transporter | NA | Successful target | TTD , DGIDB | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1 | approved | unknown |
clomipramine | serotonin transporter | NA | Successful target | TTD , DGIDB | Premature Ejaculation[MeSHID:D061686] Premenstrual syndrome[MeSHID:D011293] Stuttering[MeSHID:D013342] Narcolepsy[MeSHID:D009290] Panic Disorder[MeSHID:D016584] Off-Label Use[MeSHID:D056687] Trichotillomania[MeSHID:D014256] Obsessive-Compulsive Disorder[MeSHID:D009771] Pain[MeSHID:D010146] Mental Depression[MeSHID:D003863] Chronic pain[MeSHID:D059350] Schizophrenia[MeSHID:D012559] Depressive disorder[MeSHID:D003866] Gilles de la Tourette syndrome[MeSHID:D005879] Autistic Disorder[MeSHID:D001321] Tension Headache[MeSHID:D018781] Neuralgia[MeSHID:D009437] Cataplexy[MeSHID:D002385] Obsessive compulsive behavior[MeSHID:D003192] Obsessive-Compulsive Personality[MeSHID:D003193] Pain Disorder[MeSHID:D013001] Diabetic Neuropathies[MeSHID:D003929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1 | approved | inhibitor |
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