| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| cladribine | adenosine deaminase | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
0.35 | approved | unknown |
| cladribine | purine nucleoside phosphorylase | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inducer |
| cladribine | dna polymerase alpha catalytic subunit | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inhibitor |
| cladribine | dna polymerase epsilon catalytic subunit a | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inhibitor |
| cladribine | dna polymerase epsilon subunit 2 | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inhibitor |
| cladribine | dna polymerase epsilon subunit 3 | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inhibitor |
| cladribine | dna polymerase epsilon subunit 4 | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | inhibitor |
| cladribine | ribonucleoside-diphosphate reductase large subunit | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
2.12 | approved,investigational | inhibitor |
| cladribine | ribonucleoside-diphosphate reductase subunit m2 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
2.28 | approved,investigational | inhibitor |
| cladribine | ribonucleoside-diphosphate reductase subunit m2 b | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
3.3 | approved,investigational | inhibitor |
| cladribine | dna | small molecule | NA | drugbank | Disease[MeSHID:D004194] Lymphoma T-Cell Cutaneous[MeSHID:D016410] Chronic Lymphocytic Leukemia[MeSHID:D015451] Leukopenia[MeSHID:D007970] Thrombocytopenia[MeSHID:D013921] Hairy Cell Leukemia[MeSHID:D007943] Anemia[MeSHID:D000740] Non-Hodgkin[MeSHID:D008228] Neutropenia[MeSHID:D009503] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Multiple Sclerosis Relapsing-Remitting[MeSHID:D020529] Multiple Sclerosis[MeSHID:D009103] |
NA | approved,investigational | unknown |
| click here to return to the previous page | ||||||||