Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
chir-99021 cyclin-dependent kinase 1 NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.21 patented unknown
chir-99021 cyclin-dependent kinase 1 NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.21 patented inhibitor
chir-99021 glycogen synthase kinase-3 alpha NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.62 patented inhibitor
chir-99021 glycogen synthase kinase-3 alpha NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.62 patented unknown
chir-99021 glycogen synthase kinase-3 beta NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.33 patented inhibitor
chir-99021 glycogen synthase kinase-3 beta NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.33 patented unknown
chir-99021 extracellular signal-regulated kinase 2 NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.07 patented inhibitor
chir-99021 extracellular signal-regulated kinase 2 NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Inflammation[MeSHID:D007249]
Graft Rejection[MeSHID:D006084]		 0.07 patented unknown
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