| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.22 | approved,investigational | inhibitor |
| carvedilol | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.22 | approved,investigational | antagonist,potentiator |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.22 | approved,investigational | inhibitor,antagonist |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.22 | approved,investigational | inhibitor |
| carvedilol | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.22 | approved,investigational | antagonist,potentiator |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.22 | approved,investigational | inhibitor,antagonist |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.09 | approved,investigational | inhibitor,antagonist |
| carvedilol | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.09 | approved,investigational | antagonist |
| carvedilol | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.09 | approved,investigational | antagonist |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.09 | approved,investigational | inhibitor,antagonist |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | alpha-1d adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-1d adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | antagonist |
| carvedilol | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | antagonist |
| carvedilol | beta-1 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.95 | approved,investigational | antagonist |
| carvedilol | beta-1 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.95 | approved,investigational | antagonist |
| carvedilol | beta-2 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.34 | approved,investigational | antagonist |
| carvedilol | beta-2 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
0.34 | approved,investigational | antagonist |
| carvedilol | gap junction alpha-1 protein | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
1.26 | approved,investigational | other |
| carvedilol | gap junction alpha-1 protein | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
1.26 | approved,investigational | other |
| carvedilol | hypoxia-inducible factor 1-alpha | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | modulator |
| carvedilol | hypoxia-inducible factor 1-alpha | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | modulator |
| carvedilol | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | inward rectifier potassium channel 2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | inward rectifier potassium channel 2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | inward rectifier potassium channel 4 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | inward rectifier potassium channel 4 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | nadh dehydrogenase [ubiquinone] 1 subunit c2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | nadh dehydrogenase [ubiquinone] 1 subunit c2 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | natriuretic peptides b | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | other |
| carvedilol | natriuretic peptides b | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | other |
| carvedilol | e-selectin | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | e-selectin | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | vascular cell adhesion protein 1 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
| carvedilol | vascular cell adhesion protein 1 | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | inhibitor |
| carvedilol | vascular endothelial growth factor a | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Congestive heart failure[MeSHID:D006333] Disease[MeSHID:D004194] |
NA | approved,investigational | other |
| carvedilol | vascular endothelial growth factor a | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Ventricular Ejection Fraction[MeSHID:D013318] Heart failure[MeSHID:D006333] Ventricular Dysfunction Left[MeSHID:D018487] Myocardial Infarction[MeSHID:D009203] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,investigational | other |
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