Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
cariprazine dopamine d2 receptor small molecule Successful target TTD , drugbank , DGIDB Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 0.48 approved,investigational agonist,partial agonist
cariprazine dopamine d3 receptor small molecule Successful target TTD , drugbank , DGIDB Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 0.98 approved,investigational agonist,partial agonist
cariprazine histamine h1 receptor small molecule NA drugbank Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 NA approved,investigational antagonist
cariprazine 5-hydroxytryptamine receptor 1a small molecule NA drugbank Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 NA approved,investigational agonist,partial agonist
cariprazine 5-hydroxytryptamine receptor 2a small molecule NA drugbank Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 NA approved,investigational antagonist
cariprazine 5-hydroxytryptamine receptor 2b small molecule NA drugbank Manic[MeSHID:D001714]
Schizophrenia[MeSHID:D012559]
Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Bipolar Disorder[MeSHID:D001714]		 NA approved,investigational antagonist
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