| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| butalbital | neuronal acetylcholine receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | antagonist |
| butalbital | neuronal acetylcholine receptor subunit alpha-7 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.36 | approved,illicit | antagonist |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | potentiator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | potentiator |
| butalbital | gaba(a) receptor alpha-1 | NA | Successful target | TTD , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved | positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | positive allosteric modulator |
| butalbital | gaba(a) receptor alpha-1 | NA | Successful target | TTD , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved | unknown |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | potentiator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | potentiator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | positive allosteric modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | potentiator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | potentiator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.19 | approved,illicit | positive allosteric modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.17 | approved,illicit | positive allosteric modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.17 | approved,illicit | potentiator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.17 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.17 | approved,illicit | potentiator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.2 | approved,illicit | positive allosteric modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.2 | approved,illicit | potentiator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.2 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.2 | approved,illicit | potentiator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.22 | approved,illicit | potentiator,positive modulator |
| butalbital | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.22 | approved,illicit | potentiator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.22 | approved,illicit | positive allosteric modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.22 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.04 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.06 | approved,illicit | positive allosteric modulator,positive modulator |
| butalbital | glutamate receptor 2 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.39 | approved,illicit | antagonist |
| butalbital | glutamate receptor ionotropic, kainate 2 | small molecule | NA | drugbank , DGIDB | Headache[MeSHID:D006261] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.85 | approved,illicit | antagonist |
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