Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
buprenorphine delta-type opioid receptor small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.88 approved,illicit,investigational,vet_approved antagonist
buprenorphine kappa-type opioid receptor small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.43 approved,illicit,investigational,vet_approved antagonist,agonist
buprenorphine kappa-type opioid receptor small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.43 approved,illicit,investigational,vet_approved antagonist
buprenorphine nociceptin receptor small molecule NA drugbank Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
NA approved,illicit,investigational,vet_approved unknown
buprenorphine opioid receptor mu NA Successful target TTD , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.62 approved unknown
buprenorphine opioid receptor mu NA Successful target TTD , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.62 approved agonist
buprenorphine mu-type opioid receptor small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.62 approved,illicit,investigational,vet_approved partial agonist,agonist
buprenorphine mu-type opioid receptor small molecule NA drugbank , DGIDB Disease[MeSHID:D004194]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Migraine Disorders[MeSHID:D008881]
Pain[MeSHID:D010146]
0.62 approved,illicit,investigational,vet_approved partial agonist
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