| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| bromocriptine | alpha-1a adrenergic receptor | small molecule | NA | drugbank | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved,investigational | antagonist,agonist |
| bromocriptine | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved,investigational | antagonist,agonist |
| bromocriptine | alpha-1d adrenergic receptor | small molecule | NA | drugbank | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved,investigational | agonist |
| bromocriptine | alpha-2a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.11 | approved,investigational | agonist,antagonist |
| bromocriptine | alpha-2b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.13 | approved,investigational | agonist,antagonist |
| bromocriptine | alpha-2c adrenergic receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.11 | approved,investigational | agonist,antagonist |
| bromocriptine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.04 | approved,investigational | agonist |
| bromocriptine | dopamine d2 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.15 | approved,investigational | agonist |
| bromocriptine | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.1 | approved,investigational | agonist |
| bromocriptine | dopamine d4 receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.07 | approved,investigational | antagonist |
| bromocriptine | dopamine d5 receptor | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.14 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.06 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.1 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.11 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.06 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.13 | approved,investigational | agonist,antagonist |
| bromocriptine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
0.09 | approved,investigational | agonist |
| bromocriptine | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank | Infertility[MeSHID:D007246] Neuroleptic Malignant Syndrome[MeSHID:D009459] Testicular hypogonadism[MeSHID:D005058] Operative Surgical Procedures[MeSHID:D013514] Menstruation Disturbances[MeSHID:D008599] Galactorrhea not associated with childbirth[MeSHID:C537072] Hyperprolactinemia[MeSHID:D006966] Prolactinoma[MeSHID:D015175] Acromegaly[MeSHID:D000172] Off-Label Use[MeSHID:D056687] Galactorrhea[MeSHID:D005687] Syndrome[MeSHID:D013577] Restless Legs Syndrome[MeSHID:D012148] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Parkinson Disease[MeSHID:D010300] |
NA | approved,investigational | antagonist |
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