Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
brinzolamide carbonic anhydrase 1 small molecule NA drugbank , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.41 approved inhibitor
brinzolamide carbonic anhydrase 2 small molecule NA drugbank , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 5.53 approved inhibitor
brinzolamide carbonic anhydrase 3 small molecule NA drugbank Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
brinzolamide carbonic anhydrase 4 small molecule NA drugbank , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.7 approved inhibitor
brinzolamide carbonic anhydrase iv NA Successful target TTD , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.7 approved unknown
brinzolamide carbonic anhydrase 5a, mitochondrial small molecule NA drugbank Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
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