Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
brimonidine alpha-2a adrenergic receptor small molecule NA drugbank , DGIDB Rosacea[MeSHID:D012393]
Glaucoma
Open-Angle[MeSHID:D005902]
Erythema[MeSHID:D004890]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.9 approved agonist
brimonidine alpha-2b adrenergic receptor small molecule NA drugbank , DGIDB Rosacea[MeSHID:D012393]
Glaucoma
Open-Angle[MeSHID:D005902]
Erythema[MeSHID:D004890]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.51 approved agonist
brimonidine adrenergic receptor alpha-2c NA Successful target TTD , DGIDB Rosacea[MeSHID:D012393]
Glaucoma
Open-Angle[MeSHID:D005902]
Erythema[MeSHID:D004890]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.68 approved agonist
brimonidine adrenergic receptor alpha-2c NA Successful target TTD , DGIDB Rosacea[MeSHID:D012393]
Glaucoma
Open-Angle[MeSHID:D005902]
Erythema[MeSHID:D004890]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.68 approved unknown
brimonidine alpha-2c adrenergic receptor small molecule NA drugbank , DGIDB Rosacea[MeSHID:D012393]
Glaucoma
Open-Angle[MeSHID:D005902]
Erythema[MeSHID:D004890]
Ocular Hypertension[MeSHID:D009798]
Physiologic Intraocular Pressure[MeSHID:D007429]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.68 approved agonist
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