| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| bosutinib | tyrosine-protein kinase abl1 | small molecule | Successful target | TTD , drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
1.68 | approved | inhibitor |
| bosutinib | breakpoint cluster region protein | small molecule | NA | drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.56 | approved | inhibitor |
| bosutinib | calcium/calmodulin-dependent protein kinase type ii subunit gamma | small molecule | NA | drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.35 | approved | inhibitor |
| bosutinib | cyclin-dependent kinase 2 | small molecule | NA | drugbank | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
NA | approved | inhibitor |
| bosutinib | tyrosine-protein kinase hck | small molecule | NA | drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.17 | approved | inhibitor |
| bosutinib | tyrosine-protein kinase lyn | small molecule | NA | drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.16 | approved | inhibitor |
| bosutinib | dual specificity mitogen-activated protein kinase kinase 1 | small molecule | NA | drugbank | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
NA | approved | inhibitor |
| bosutinib | dual specificity mitogen-activated protein kinase kinase 2 | small molecule | NA | drugbank | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
NA | approved | inhibitor |
| bosutinib | mitogen-activated protein kinase kinase kinase 2 | small molecule | NA | drugbank | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
NA | approved | inhibitor |
| bosutinib | proto-oncogene tyrosine-protein kinase src | small molecule | NA | drugbank , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.39 | approved | inhibitor |
| bosutinib | proto-oncogene c-src | NA | Successful target | TTD , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.39 | approved | unknown |
| bosutinib | proto-oncogene c-src | NA | Successful target | TTD , DGIDB | Blast Phase[MeSHID:D001752] Philadelphia Chromosome[MeSHID:D010677] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of breast[MeSHID:D001943] |
0.39 | approved | inhibitor |
| click here to return to the previous page | ||||||||