Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
bifeprunox dopamine d2 receptor small molecule Successful target TTD , drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.24 investigational,discontinued in phase 3 unknown
bifeprunox dopamine d2 receptor small molecule Successful target TTD , drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.24 investigational,discontinued in phase 3 partial agonist
bifeprunox 5-hydroxytryptamine receptor 1a small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.51 investigational partial agonist
bifeprunox 5-ht 1a receptor NA Successful target TTD , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.51 discontinued in phase 3 unknown
bifeprunox 5-hydroxytryptamine receptor 1a small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.51 investigational unknown
bifeprunox 5-ht 1a receptor NA Successful target TTD , DGIDB Schizophrenia[MeSHID:D012559]
Psychotic Disorders[MeSHID:D011618]
Parkinson Disease[MeSHID:D010300]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.51 discontinued in phase 3 partial agonist
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