Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
atorvastatin | aryl hydrocarbon receptor | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | approved | agonist |
atorvastatin | aryl hydrocarbon receptor | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | agonist |
atorvastatin | dipeptidyl peptidase 4 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
atorvastatin | dipeptidyl peptidase 4 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | approved | inhibitor |
atorvastatin | histone deacetylase 2 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
atorvastatin | histone deacetylase 2 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | approved | inhibitor |
atorvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.01 | approved | unknown |
atorvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.01 | approved | inhibitor |
atorvastatin | 3-hydroxy-3-methylglutaryl-coenzyme a reductase | small molecule | NA | drugbank , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.01 | approved | inhibitor |
atorvastatin | 3-hydroxy-3-methylglutaryl-coenzyme a reductase | small molecule | NA | drugbank , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.01 | approved | inhibitor |
atorvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.01 | approved | inhibitor |
atorvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.01 | approved | unknown |
atorvastatin | nuclear receptor subfamily 1 group i member 3 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | ligand |
atorvastatin | nuclear receptor subfamily 1 group i member 3 | small molecule | NA | drugbank | Diabetes Mellitus[MeSHID:D003920] Hospitalization[MeSHID:D006760] Angina Pectoris[MeSHID:D000787] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Stable angina[MeSHID:D060050] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Prescription of drug (procedure)[MeSHID:D011307] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Diabetes Mellitus Non-Insulin-Dependent[MeSHID:D003924] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Homozygote[MeSHID:D006720] Congestive heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Disease[MeSHID:D004194] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | approved | ligand |
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