| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| asenapine | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved | antagonist |
| asenapine | alpha-2a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.07 | approved | antagonist |
| asenapine | alpha-2b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | antagonist |
| asenapine | alpha-2c adrenergic receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | antagonist |
| asenapine | beta-1 adrenergic receptor | small molecule | NA | drugbank | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| asenapine | beta-2 adrenergic receptor | small molecule | NA | drugbank | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| asenapine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved | antagonist |
| asenapine | dopamine d2 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | antagonist |
| asenapine | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.15 | approved | antagonist |
| asenapine | dopamine d4 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved | antagonist |
| asenapine | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | antagonist |
| asenapine | histamine h2 receptor | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.37 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | antagonist,agonist |
| asenapine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved | antagonist,agonist |
| asenapine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 5a | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.68 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.3 | approved | antagonist |
| asenapine | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank , DGIDB | Manic Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Psychotic Disorders[MeSHID:D011618] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved | antagonist |
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