| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| arsenic trioxide | rac-alpha serine/threonine-protein kinase | small molecule | NA | drugbank | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inducer |
| arsenic trioxide | g1/s-specific cyclin-d1 | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | antagonist |
| arsenic trioxide | cyclin-dependent kinase inhibitor 1 | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | unknown |
| arsenic trioxide | histone deacetylase 1 | small molecule | NA | drugbank | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | unknown |
| arsenic trioxide | inhibitor of nuclear factor kappa-b kinase beta | NA | Clinical trial target | TTD , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved | unknown |
| arsenic trioxide | inhibitor of nuclear factor kappa-b kinase subunit beta | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inducer |
| arsenic trioxide | transcription factor ap-1 | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inducer |
| arsenic trioxide | mitogen-activated protein kinase 1 | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inducer |
| arsenic trioxide | mitogen-activated protein kinase 3 | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inducer |
| arsenic trioxide | protein pml | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | unknown |
| arsenic trioxide | thioredoxin reductase 1, cytoplasmic | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
NA | approved,investigational | inhibitor |
| arsenic trioxide | thioredoxin reductase 1, cytoplasmic | small molecule | NA | drugbank , DGIDB | Acute Promyelocytic Leukemia[MeSHID:D015473] Chromosomal translocation[MeSHID:D014178] Gene Expression[MeSHID:D015870] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] |
10.61 | approved,investigational | inhibitor |
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