Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
arbaclofen placarbil gamma-aminobutyric acid type b receptor subunit 1 small molecule NA drugbank , DGIDB Muscle Spasticity[MeSHID:D009128]
Multiple Sclerosis[MeSHID:D009103]
Gastroesophageal reflux disease[MeSHID:D005764]
Spasm[MeSHID:D013035]
Fragile X Syndrome[MeSHID:D005600]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Alcoholic Intoxication
Chronic[MeSHID:D000437]		 45.47 investigational agonist
arbaclofen placarbil gamma-aminobutyric acid type b receptor subunit 2 small molecule NA drugbank , DGIDB Muscle Spasticity[MeSHID:D009128]
Multiple Sclerosis[MeSHID:D009103]
Gastroesophageal reflux disease[MeSHID:D005764]
Spasm[MeSHID:D013035]
Fragile X Syndrome[MeSHID:D005600]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Alcoholic Intoxication
Chronic[MeSHID:D000437]		 57.29 investigational agonist
arbaclofen placarbil gaba(a) receptor gamma-3 NA Successful target TTD , DGIDB Muscle Spasticity[MeSHID:D009128]
Multiple Sclerosis[MeSHID:D009103]
Gastroesophageal reflux disease[MeSHID:D005764]
Spasm[MeSHID:D013035]
Fragile X Syndrome[MeSHID:D005600]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Alcoholic Intoxication
Chronic[MeSHID:D000437]		 NA phase 3 unknown
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