| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| amuvatinib | receptor-type tyrosine-protein kinase flt3 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.38 | investigational | inhibitor |
| amuvatinib | receptor-type tyrosine-protein kinase flt3 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.38 | investigational | unknown |
| amuvatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.63 | investigational | inhibitor |
| amuvatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.63 | investigational | unknown |
| amuvatinib | hepatocyte growth factor receptor | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.5 | investigational | unknown |
| amuvatinib | hepatocyte growth factor receptor | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.5 | investigational | inhibitor |
| amuvatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.41 | investigational | unknown |
| amuvatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.41 | investigational | inhibitor |
| amuvatinib | dna repair protein rad51 homolog 1 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
9.09 | investigational | unknown |
| amuvatinib | proto-oncogene tyrosine-protein kinase receptor ret | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.41 | investigational | unknown |
| amuvatinib | proto-oncogene tyrosine-protein kinase receptor ret | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] DNA Repair[MeSHID:D004260] Cells[MeSHID:D002477] Genetic Selection[MeSHID:D012641] Hepatic methionine adenosyltransferase deficiency[MeSHID:C564683] |
0.41 | investigational | inhibitor |
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