Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
amphetamine alpha adrenergic receptor small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.12 approved,illicit,investigational agonist
amphetamine alpha adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine alpha adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine alpha adrenergic receptor small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.05 approved,illicit,investigational agonist
amphetamine alpha adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine alpha adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine beta adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine beta adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine beta adrenergic receptor small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist
amphetamine cocaine- and amphetamine-regulated transcript protein small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 7.43 approved,illicit,investigational agonist
amphetamine dopamine d2 receptor small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.05 approved,illicit,investigational binder
amphetamine monoamine oxidase small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational inhibitor
amphetamine monoamine oxidase small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational inhibitor
amphetamine amine oxidase [flavin-containing] b small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational inhibitor
amphetamine synaptic vesicular amine transporter small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.27 approved,illicit,investigational inhibitor
amphetamine sodium-dependent noradrenaline transporter small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational agonist,substrate
amphetamine sodium-dependent dopamine transporter small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.78 approved,illicit,investigational negative modulator
amphetamine sodium-dependent serotonin transporter small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational binder
amphetamine trace amine-associated receptor 1 small molecule NA drugbank , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.99 approved,illicit,investigational agonist
amphetamine trace amine-associated receptor-1 NA Successful target TTD , DGIDB Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.99 approved unknown
amphetamine vesicular monoamine transporter 2 (vmat2) small molecule NA drugbank Depressive disorder[MeSHID:D003866]
Disease[MeSHID:D004194]
Attention deficit hyperactivity disorder[MeSHID:D001289]
Reproductive History[MeSHID:D017584]
Hand[MeSHID:D006225]
Genetic Heterogeneity[MeSHID:D018740]
Narcolepsy[MeSHID:D009290]
Sleep Disorders[MeSHID:D012893]
Obesity[MeSHID:D009765]
Mental Depression[MeSHID:D003863]
Neurodevelopmental Disorders[MeSHID:D065886]
Sleep[MeSHID:D012890]
Hypersomnia[MeSHID:D006970]
Chronic disease[MeSHID:D002908]
Chronic pain[MeSHID:D059350]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,illicit,investigational unknown
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