Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
amibegron adrenergic receptor beta-3 NA Successful target TTD , DGIDB Irritable Bowel Syndrome[MeSHID:D043183]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]
Obesity[MeSHID:D009765]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Unipolar Depression[MeSHID:D003866]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Major Depressive Disorder[MeSHID:D003865]
Mood Disorders[MeSHID:D019964]
5.03 discontinued in phase 3 agonist
amibegron adrenergic receptor beta-3 NA Successful target TTD , DGIDB Irritable Bowel Syndrome[MeSHID:D043183]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]
Obesity[MeSHID:D009765]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Unipolar Depression[MeSHID:D003866]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Major Depressive Disorder[MeSHID:D003865]
Mood Disorders[MeSHID:D019964]
5.03 discontinued in phase 3 unknown
amibegron beta-3 adrenergic receptor small molecule NA drugbank , DGIDB Irritable Bowel Syndrome[MeSHID:D043183]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]
Obesity[MeSHID:D009765]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Unipolar Depression[MeSHID:D003866]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Major Depressive Disorder[MeSHID:D003865]
Mood Disorders[MeSHID:D019964]
5.03 investigational unknown
amibegron beta-3 adrenergic receptor small molecule NA drugbank , DGIDB Irritable Bowel Syndrome[MeSHID:D043183]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]
Obesity[MeSHID:D009765]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Unipolar Depression[MeSHID:D003866]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Major Depressive Disorder[MeSHID:D003865]
Mood Disorders[MeSHID:D019964]
5.03 investigational agonist
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