Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
ambrisentan endothelin a receptor NA Successful target TTD , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Ability[MeSHID:D001076]
Hospitalization[MeSHID:D006760]
Connective Tissue Diseases[MeSHID:D003240]
Disease Progression[MeSHID:D018450]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 10.61 approved unknown
ambrisentan endothelin a receptor NA Successful target TTD , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Ability[MeSHID:D001076]
Hospitalization[MeSHID:D006760]
Connective Tissue Diseases[MeSHID:D003240]
Disease Progression[MeSHID:D018450]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 10.61 approved antagonist
ambrisentan endothelin-1 receptor small molecule NA drugbank , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Ability[MeSHID:D001076]
Hospitalization[MeSHID:D006760]
Connective Tissue Diseases[MeSHID:D003240]
Disease Progression[MeSHID:D018450]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 10.61 approved,investigational antagonist
ambrisentan endothelin b receptor small molecule NA drugbank , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Ability[MeSHID:D001076]
Hospitalization[MeSHID:D006760]
Connective Tissue Diseases[MeSHID:D003240]
Disease Progression[MeSHID:D018450]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 12.73 approved,investigational antagonist
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