| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| afimoxifene | estrogen receptor alpha | small molecule | NA | drugbank , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
0.15 | investigational | modulator |
| afimoxifene | estrogen receptor | NA | Successful target | TTD , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
0.15 | phase 2 | unknown |
| afimoxifene | estrogen receptor | NA | Successful target | TTD , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
0.15 | phase 2 | modulator |
| afimoxifene | estrogen receptor alpha | small molecule | NA | drugbank , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
0.15 | investigational | unknown |
| afimoxifene | estrogen receptor beta | small molecule | NA | drugbank , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
0.14 | investigational | modulator |
| afimoxifene | steroid hormone receptor err1 | small molecule | NA | drugbank | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
NA | investigational | inhibitor |
| afimoxifene | estrogen-related receptor gamma | small molecule | NA | drugbank , DGIDB | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
1.4 | investigational | antagonist |
| afimoxifene | nuclear receptor subfamily 1 group i member 2 | small molecule | NA | drugbank | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
NA | investigational | unknown |
| afimoxifene | sex hormone-binding globulin | small molecule | NA | drugbank | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
NA | investigational | unknown |
| afimoxifene | trefoil factor 1 | small molecule | NA | drugbank | Gynecomastia[MeSHID:D006177] Mastodynia[MeSHID:D059373] Breast Diseases[MeSHID:D001941] Keloid[MeSHID:D007627] Menstrual cycle[MeSHID:D008597] Breast Fibrocystic Disease[MeSHID:D005348] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Ductal Carcinoma[MeSHID:D044584] Malignant neoplasm of breast[MeSHID:D001943] |
NA | investigational | unknown |
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