Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
abt-263 apoptosis regulator bcl-2 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Primary Myelofibrosis[MeSHID:D055728]
Chronic Lymphocytic Leukemia[MeSHID:D015451]
Malignant Neoplasms[MeSHID:D009369]
Relapse[MeSHID:D012008]
0.72 phase 3 unknown
abt-263 apoptosis regulator bcl-xl NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Primary Myelofibrosis[MeSHID:D055728]
Chronic Lymphocytic Leukemia[MeSHID:D015451]
Malignant Neoplasms[MeSHID:D009369]
Relapse[MeSHID:D012008]
2.65 phase 3 unknown
abt-263 apoptosis regulator bcl-w NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Primary Myelofibrosis[MeSHID:D055728]
Chronic Lymphocytic Leukemia[MeSHID:D015451]
Malignant Neoplasms[MeSHID:D009369]
Relapse[MeSHID:D012008]
2.65 phase 3 unknown
abt-263 g1/s-specific cyclin-d1 NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Primary Myelofibrosis[MeSHID:D055728]
Chronic Lymphocytic Leukemia[MeSHID:D015451]
Malignant Neoplasms[MeSHID:D009369]
Relapse[MeSHID:D012008]
0.27 phase 3 unknown
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